Subjects | 1115 | 37 | | | | |
Age at PEA years | 61 (22) | 81 (2) | | | | |
Gender female | 517 (46) | 17 (46) | 1.000 | | | |
Comorbidities | | | | | | |
COPD | 78 (7) | 2 (5) | 1.000 | | | |
Diabetes | 94 (9) | 2 (6) | 0.950 | | | |
Atrial fibrillation/flutter | 91 (9) | 5 (14) | 0.810 | | | |
Ischaemic heart disease | 124 (12) | 7 (19) | 0.560 | | | |
Malignancy | 85 (8) | 4 (11) | 1.000 | | | |
Systemic hypertension | 307 (30) | 10 (28) | 1.000 | | | |
CAMPHOR score# | | | | | | |
Symptoms | 13±10 | 12±9 | 1.000 | 4±8 | 4±7 | 0.860 |
Activity | 11±9 | 14±8 | 0.260 | 6±9 | 9±6 | 0.300 |
Quality of life | 11±11 | 11±11 | 0.870 | 4±10 | 6±8 | 1.000 |
WHO functional class¶ % | | | 0.046 | | | 0.450 |
Class 1 | 0 | 0 | | 28 | 22 | |
Class 2 | 14 | 3 | | 47 | 40 | |
Class 3 | 73 | 70 | | 23 | 33 | |
Class 4 | 13 | 26 | | 1 | 4 | |
6MWD m | 290±216 | 227±210 | 0.051 | 360±164 | 286±92 | 0.020 |
mPAP mmHg | 45±15 | 42±12 | 0.560 | 25±13 | 28±12 | 0.560 |
PVR dynes·s·cm−5 | 666±479 | 743±462 | 0.310 | 235±212 | 297±294 | 0.081 |
CI L·min−1·m−2 | 2.2±0.8 | 1.9±0.8 | 0.020 | 2.3±0.7 | 2.3±0.8 | 0.810 |
Type of surgical disease+ % | | | 1.000 | | | |
Type 1 | 14 | 14 | | | | |
Type 2 | 58 | 59 | | | | |
Type 3 | 26 | 27 | | | | |
Type 4 | 3 | 0 | | | | |
Bypass time min | 323±65 | 305±51 | 0.020 | | | |
Arrest time min | 37±15 | 33±13 | 0.230 | | | |
Concomitant surgery: total | 123 (11) | 10 (27) | 0.042 | | | |
CABG | 76 (7) | 7 (19) | | | | |
PFO/ASD closure | 34 (3) | 1 (3) | | | | |
MVR | 12 (2) | 0 (0) | | | | |
AVR | 8 (1) | 2 (5) | | | | |
Complications: total§ | 277 (32) | 12 (35) | 1.000 | | | |
ECMO | 60 (6) | 2 (6) | | | | |
Pneumonia | 110 (12) | 6 (18) | | | | |
Re-intubation | 91 (10) | 3 (9) | | | | |
Renal replacement therapy | 52 (6) | 0 (0) | | | | |
Return to theatre | 80 (9) | 2 (6) | | | | |
Tracheotomy | 61 (6) | 1 (3) | | | | |
Length of stay days | | | | | | |
Intensive care unit | 4±3 | 5±5 | 0.310 | | | |
Total hospital | 14±10 | 19±7 | 0.020 | | | |
In-hospital mortality % | 4 | 8 | 0.510 | | | |
Residual PHƒ | | | | | | |
mPAP ≥25 mmHg | | | | 463 (51) | 18 (62) | 1.000 |
mPAP ≥30 mmHg | | | | 309 (34) | 13 (44) | 0.560 |
mPAP≥38 mmHg and PVR ≥425 dynes·s·cm−5 | | | | 101 (11) | 2 (7) | 0.930 |
Survival % | | | | | | |
1 year | | | | 91.8 | 83.5 | 0.020 |
3 years | | | | 88.2 | 76.4 | |
5 years | | | | 84.4 | 69.4 | |