Optimal anticoagulant regime |
Cancer-associated incidental PE | LMWH for the first 6 months |
Alternatively: switch to VKA if subcutaneous therapy is not tolerated |
Non-cancer-associated incidental PE | DOAC |
Alternatively: conventional treatment with VKA if DOAC is contraindicated |
Optimal treatment duration |
Cancer- associated incidental PE | At least 6 months and beyond for the duration of active disease |
Non-cancer-associated provoked incidental PE | 3 months |
Non-cancer-associated unprovoked incidental PE | At least 3 months, indefinite if risk of bleeding is low |
Outpatient treatment |
All incidental PE | In the case of an outpatient, consider initiation of anticoagulant treatment at home, provided that adequate instructions are given to the patient |
In the case of an inpatient, initiate anticoagulant therapy in the hospital |