Background: The aim of this study is to describe the clinical similarities and differences between atopic and non-atopic asthmatics in children.
Methods: In this cross-sectional study, 95 asthmatics (75 allergics and 20 nonallergics) children were included and the demographic, clinical, and familial characteristics were compared across the groups.
Results: There was no significant difference between important factors like sex (p=1.00), age of onset (0.75) and severity (0.70), and family history among two groups (P > 0.05). Patients with allergic asthma were significantly older than those with non- allergic asthma (11.28 ± 3.19 and 9.75 ± 2.35 years respectively, p <0.05).
Conclusion: The controversy over the presence of non-atopic asthma as a completely distinct clinical entity in children lingers. Our study suggests that phenotypes of allergic and non-allergic asthma in children are not highly distinct, along with the immunological similarities recently published.
- Copyright ©the authors 2016