Patients n | 300 | 80 | |
Age years | 51.1±16.6 | 64.2±13.8 | <0.001 |
Males | 27 (22–32) | 36 (27–47) | 0.09 |
BMI kg·m−2 | 25.5±5.5 | 28.1±5.8 | <0.001 |
Medical history | | | |
Diabetes | 10 (7–14) | 30 (21–41) | <0.001 |
Hypertension | 19 (15–24) | 41 (31–52) | <0.001 |
Dyslipidaemia | 10 (7–14) | 33 (23–43) | <0.001 |
Smoking >1 pack-year | 47 (41–53) | 59 (48–69) | 0.08 |
Left valvular disease worse than mild | 2 (1–4) | 43 (32–53) | <0.001 |
Coronary artery disease | 7 (4–10) | 31 (22–42) | <0.001 |
Left heart disease | 8 (6–12) | 58 (47–68) | <0.001 |
ECG | | | |
Left atrial dilation | 9 (7–13) | 5 (2–13) | 0.27 |
SV1+RV6 mm | 10.8±5.5 | 17.3±9.0 | <0.001 |
Echocardiography | | | |
Left atrial dilation | 24 (20–29) | 86 (77–92) | <0.001 |
Left valvular disease worse than mild | 9 (7–13) | 65 (54–75) | <0.001 |
Right heart catheterisation | | | |
Right atrial pressure mmHg | 9±9 | 12±7 | 0.08 |
PAP mmHg | 48±15 | 42±12 | 0.02 |
Cardiac output L·min−1 | 5.09±2.09 | 5.37±2.18 | 0.45 |
Heart rate beats·min−1 | 81±14 | 80±17 | 0.74 |
PVR dyn·s·cm−5 | 792±545 | 435±323 | <0.01 |
Wedge pressure mmHg | 9±5 | 21±6 | <0.001 |
TPG mmHg | 40±16 | 21±12 | <0.001 |
Mixed venous O2 saturation % | 65±11 | 64±10 | 0.65 |