Subjects n | 40 | 10 | 8 |
Age years | 23±14 | 22±7 | 56±17 |
Sex male/female | 19/21 | 4/6 | 5/3 |
CRP mg·dL−1 | 0.8±0.5 | n.d. | 1.2±0.8 |
WBC 109·L−1 | 11±7 | 7±4 | 10±6 |
Total IgE kUI·L−1 | 49±34 | n.d. | 44±27 |
FEV1 % pred | 66±15 | n.d. | 55±20 |
MEF25 % pred | 39±27 | n.d. | 29±16 |
Neutrophils in sputum % | 82±29 | 15±9 | 58±31 |
Eosinophils in sputum % | 3±2.8 | 0.6±0.4 | 1.9±0.7 |
Pseudomonas aeruginosa | 18 | n.d. | 2 |
Aspergillus spp. | 22 | n.d. | 3 |
IgE specific to Aspergillus fumigatus kU·L−1 | 2.3±1.6 | n.d. | 0.8±0.5 |
IgG specific to A. fumigatus mg·L−1 | 59±35 | n.d. | 37±19 |
A. fumigatus precipitins | 2/40 | n.d. | 0/3 |
Candida spp. | 20 | n.d. | 2 |
Aspergillus spp. and Candida spp. co-colonisation | 10 | n.d. | 0 |
Staphylococcus aureus | 11 | n.d. | 0 |
Haemophilus influenzae | 4 | n.d. | 0 |
Achromobacter xylosoxidans | 5 | n.d. | 0 |
Stenotrophomonas maltophilia | 6 | n.d. | 0 |
Inhaled antibiotics | 18 | 0 | 2 |
Inhaled corticosteroids | 16 | 0 | 2 |
Dornase-α/DNase | 15 | 0 | 0 |
Azithromycin | 11 | 0 | 1 |
ΔF508 homozygous/heterozygous/other | 20/13/7 | n.d. | n.d. |