| TB isolate¶ | TB relapse isolate+ |
| MGIT 960 phenotype | Resistance genotype | MGIT 960 phenotype | Resistance genotype |
Isoniazid mg·L−1 | | katG Ser315Thr inhA wild type | | katG Ser315Thr inhA wild type |
0.1 | Resistant | Resistant |
1.0 | Resistant | Resistant |
3.0 | Resistant | Resistant |
10.0 | Resistant | Resistant |
Rifampicin mg·L−1 | | rpoB Ser531Leu | | rpoB Ser531Leu |
1.0 | Resistant | Resistant |
4.0 | Resistant | Resistant |
20.0 | Resistant | Resistant |
Rifabutin mg·L−1 | | |
0.1 | Resistant | Resistant |
0.4 | Resistant | Resistant |
2.0 | Not performed | Resistant |
Ethambutol mg·L−1 | | Not applicable | | Not applicable |
5.0 | Susceptible | Susceptible |
12.5 | Susceptible | Susceptible |
50.0 | Susceptible | Susceptible |
Streptomycin mg·L−1 | | rpsL Lys88Arg rrs wild type (530 region) | | rpsL Lys88Arg rrs wild type (530 region) |
1.0 | Resistant | Resistant |
4.0 | Susceptible | Susceptible |
20.0 | Susceptible | Susceptible |
Amikacin mg·L−1 | | rrs wild type (1400 region) | | rrs wild type (1400 region) |
1.0 | Susceptible | Susceptible |
4.0 | Susceptible | Susceptible |
20.0 | Susceptible | Susceptible |
Capreomycin mg·L−1 | | rrs wild type (1400 region) tlyA wild type | | rrs wild type (1400 region) tlyA wild type |
2.5 | Susceptible | Susceptible |
5.0 | Susceptible | Susceptible |
25.0 | Susceptible | Susceptible |
Ethionamide mg·L−1 | | ethA Ser266Arg inhA wild type | | ethA Ser266Arg |
5.0 | Resistant | Resistant |
10.0 | Resistant | Resistant |
25.0 | Resistant | Resistant |
Linezolid mg·L−1 | | rrl A2572C rrl G2576T | | rrl A2572C rrl G2576T |
1.0 | Resistant | Resistant |
4.0 | Resistant | Resistant |
16.0 | Susceptible | Susceptible |
Moxifloxacin mg·L−1 | | gyrA Asp94Tyr | | gyrA Asp94Tyr |
0.25 | Resistant | Resistant |
0.5 | Resistant | Resistant |
2.5 | Susceptible | Resistant |
7.5 | Not performed | Susceptible |
Para-aminosalicylic acid mg·L−1 | | Not applicable | | Not applicable |
4 | Susceptible | Susceptible |
16 | Susceptible | Susceptible |
64 | Susceptible | Susceptible |
Cycloserine mg·L−1 | | Not applicable | | Not applicable |
50 | Susceptible | Susceptible |
Pyrazinamide mg·L−1 | | pncA Gly107 Stop | | pncA Gly107Stop |
100 | Resistant | Resistant |
Clofazimine mg·L−1 | | Rv0678 wild type | | Rv0678 fMet1Ala |
0.5 | Resistant | Resistant |
1.0 | Susceptible | Resistant |
4.0 | Susceptible | Resistant |
Bedaquiline | | atpE wild type Rv0678 wild type | | atpE wild type Rv0678 fMet1Ala |
Not available | Not available | Not applicable |