Abstract
Background
Although the most effective treatment for lung cancer remains complete surgical resection with curative intent, it is unclear how pulmonary resection has influenced physical function during early postoperative period after surgery.
Objectives
The purpose of this study was to identify the impact of surgery for lung cancer on skeletal muscle function and exercise capacity.
Methods
Handgrip and Quadriceps force (HF, QF) and six minute walking distance (6MWD) were assessed in 168 patients (108 males, age 68±8) before and 1 week after surgery, lung resection by video assisted thoracotomy surgery or thoracotomy. All patients received standard perioperative physiotherapy.
Results
Significant decreases were found in HF (29.5±9.2kg vs. 28.3±9.0kg, respectively; P<.05), QF (32.6±12.8kg vs. 30.8±11.8kg, P<.05) and 6MWD (506±82m vs. 454±88m, P<.0001) from before to 1 week after surgery. Prevalence of postoperative pulmonary complications (40% vs. 7%, P<.0001), duration of chest tube drainage (5±days vs. 4±days, P<.05) and type of surgery (the percentage of thoracotomy, 64% vs. 48%, P<.05) were significant different in patients with a reduction in 6MWD compared to non-decreased.
Conclusions
Skeletal muscle strength and functional exercise capacity during the early postoperative period after lung resection decreased , and patients who had lower 6MWD were significantly more pulmonary complications and longer duration of chest tube drainage. These results suggest that routine exercise testing and training in early postoperative period after surgery are needed for improving physical function and activities.
- © 2014 ERS