Abstract
The aim of the research is to study the state of health of children recently born of women with bronchial asthma. We analyzed 340 cases over the last 20 years (group 1). The comparison group includes 140 newborns of women who do not have chronic respiratory diseases (group 2). Pregnant women of group 1 showed greater incidence of complications than in the control group. Pregnancy with bronchial asthma caused the increase of diagnosed placental insufficiency, chronic intrauterine fetal hypoxia, and premature birth. Pregnancy complications are often observed in patients with uncontrolled course of asthma. Physical development of newborns in group 1 was lower than in group 2. The frequency of disharmonious development was more common in children of mothers with severe asthma (p <0,05), indicating the intrauterine fetal suffering . The prevailing diseases in newborns of group 1 include cerebral ischemia (65.2 %), localized inflammation of the skin (37.2%), post hypoxic cardiomyopathy (22%), intrauterine growth retardation (19.3 %), which differed significantly from the corresponding figures of group 2. The polyorganic character of system damage was found in 70% of group 1 infants, and only in 11% of group 2. Severity status of newborns in group 1 correlated with worsening of asthma during pregnancy, the frequency of birth of healthy children being significantly reduced. Thus, the perinatal outcomes in patients with asthma depend on the severity of the disease and the level of control during the gestation period. Babies born to mothers with asthma are characterized by high frequency of disharmonious development, greater polyorganic morbidity of systems, which necessitate preventive measures during the gestational period.
- © 2014 ERS