Abstract
Background: Community-acquired pneumonia may course as a severe infection with poor outcome. Mixed etiology pneumonia has been associated with worse prognosis and higher mortality.
Objective: To characterize clinical presentation and prognosis of polimicrobial CAP.
Methods: A prospective multicentric cohort study was performed in 13 hospitals.
Results: 4070 patients were included and etiological diagnosis was reached in 1506 (37%). The causal microorganisms found are depicted in the graph.
The most frequent association in mixed etiology was two bacteria (S. pneumoniae plus another (71.1%)). Initial severity measured by prognostic scales, sepsis criteria, radiological findings and requirement of ICU admission was higher in polimicrobial CAP. Mortality was significantly higher in that group.
Conclusions: Mixed etiology CAP most common is caused by S. pneumoniae plus another bacteria (71.1%), courses with higher initial severity, more ICU requirement and poor outcome.
- © 2014 ERS