Abstract
Untreated OSA is a risk factor for cardiovascular morbidity. Arterial hypertension is one of the most frequent OSA complications. The aim of study was to compare hypertensive OSA pts and subjects without arterial hypertension. We studied 1164 OSA pts, mean age = 56.4±10.4 years, with obesity (BMI = 34.2±6.4 kg/m2) and moderate to severe disease (AHI = 39.6±21.7). We found 307 normotensive OSA pts (26.4%) and 857 OSA pts with arterial hypertension (73.6%). Comparison of both groups is shown in the table.
Logistic regression revealed that: diabetes (OR- 3.05; 95%CI – 1.88-4.95; p<0.0001), BMI > 30 vs ≤ 30 (OR- 2.34; 95%CI – 1.67-3.28;p<0.0001), NT-proBNP > 125 vs ≤ 125 pg/ml (OR – 1.85; 95%CI – 1.23-2.79; p=0.003), hyperuricaemia (OR-1.83; 95%CI – 1.28-2.63; p=0.0009) and nocturia ≥ 2 vs < 2 (OR-1.50; 95%CI – 1.24-4.16; p=0.007) were independent predictors of arterial hypertension after adjusting for CAD, stroke, HF, AF, COPD, AHI > 30 vs ≤30, T90 >30 vs ≤ 30.
Conclusions: Arterial hypertension was very common in our group of OSA pts. The highest risk of arterial hypertension was related to diabetes and obesity.
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