Abstract
Aim: to investigate the effectiveness of treatment for wheezing in preschool children based on ERS task force.
Material and Methods: Preschooler children with recurrent wheezing were classified as viral episodic wheeze (VEW) and multiple trigger wheeze (MTW) with respect to ERS task force and their treatments were arranged. Patients were evaluated at the beginning, at the end of the first month, and third month for the effectiveness of treatment by determining control levels according to the criteria in Global Initiative for Asthma Guideline for “asthma control levels”.
Results: 59 (56.7%) of 104 patients included in this study are boys and 45 (45.3%) of them are girls. 70 (67.3%) patients are classified as VEW and 34 (32.7%) as MTW. The mean age of VEW and MTW groups are 27.9±17.3 and 34.5±18.3, respectively. In MTW group, blood eosinophil levels and serum total IgE levels were found to be statistically significantly higher than VEW group. “The average numbers of symptom free days during 1 month before the treatment” in VEW and MTW groups were determined as statistically significantly lower compared to the 1st and 3rd months’ averages. In the 3rd month of the treatment, total control has been achieved in 81.4% of VEW group and in 76.5% of MTW group. Controller medications were changed in 7 (6.7%) cases because of insufficient control (2 cases (5.8%) MTW and 5 cases (7.1%) from VEW group).
Conclusion: Phenotype based classification which is a practical approach can be used in evaluation and treatment of preschool children with recurrent wheezing.
Reference:
1.Brand PL et al. Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J. 2008 Oct;32(4):1096-110.
- © 2013 ERS