Figures
- Figure 1–
Proportion of children with positive tuberculin skin test (TST), interferon (IFN)-γ and IFN-γ-induced protein (IP)-10 results by sputum grade of the index case.
- Figure 2–
Concordance between tuberculin skin test (TST), interferon (IFN)-γ and IFN-γ induced protein (IP)-10 results by sputum grade of the index case. a) TST versus IFN-γ; b) TST versus IP-10; c) IFN-γ versus IP-10.
- Figure 3–
Proportion of children with positive tuberculin skin test (TST); positive interferon (IFN)-γ and negative TST; and positive IFN-γ-induced protein (IP)-10 and negative TST and IFN-γ by sputum grade of the index case.
Tables
- Table 1– Tuberculin skin test (TST), interferon (IFN)-γ and IFN-γ-induced protein (IP)-10 results in children by sputum grade of the index case
Bacilli count of the adult Controls Total +++ ++ + Scanty Subjects 15 109 188 18 156 486 TST Positive 13 (86.7) 46 (43) 95 (54.6) 14 (82.4) 20 (12.8) 469 Intermediate 0 19 (17.8) 28 (16.1) 1 (5.9) 15 (9.6) Negative 2 (13.3) 42 (39.3) 51 (29.3) 2 (11.8) 121 (77.6) IFN-γ Positive 8 (57.1) 53 (50.5) 74 (43.8) 3 (17.6) 20 (13.1) 458 Indeterminate 5 (35.7) 13 (12.4) 24 (14.2) 10 (58.8) 25 (16.3) Negative 1 (7.1) 39 (37.1) 71 (42) 4 (23.5) 108 (70.6) IP-10# Positive 7 (50) 60 (59.4) 96 (55.8) 4 (23.5) 9 (5.8) 458 Negative 7 (50) 41 (40.6) 76 (44.2) 13 (76.5) 145 (94.2) Data are presented as n or n (%). #: IP-10 positive grading ≥3,022 pg·mL−1, as calculated by the receiver operating characteristic curve.
- Table 2– Tuberculin skin test (TST) and interferon (IFN)-γ results in children by bacille Calmette–Guérin (BCG) and HIV status
Contacts Controls BCG+ BCG- HIV+ HIV- BCG+ BCG- HIV+ HIV- TST Positive 135 (56) 29 (47.5) 12 (48) 123 (56.7) 16 (13.3) 2 (5.9) 0 20 (13.1) Intermediate 38 (15.8) 9 (14.8) 5 (20) 24 (11) 12 (1) 3 (8.8) 0 15 (9.8) Negative 68 (28.2) 23 (37.7) 8 (32) 70 (32.3) 92 (76.6) 29 (85.3) 3 (100) 118 (77.1) IFN-γ Positive 105 (46) 24 (36.4) 10 (41.6) 93 (41.5) 13 (10.9) 6 (18.2) 0 20 (13.3) Indeterminate 32 (14) 20 (30.3) 4 (16.7) 44 (19.6) 23 (19.3) 2 (6) 0 25 (16.7) Negative 91 (40) 22 (33.3) 10 (41.6) 87 (38.8) 83 (69.8) 25 (75.8) 3 (100) 105 (70) Data are presented as n (%).
Vol 41 Issue 3
Table of Contents
Use of tuberculin skin test, IFN-γ release assays and IFN-γ-induced protein-10 to identify children with TB infection
