Abstract
Objective: To compare the results of surgical lung volume reduction in patients with COPD with the results of endobronchial lung volume reduction valve.
Materials and methods: endobronchial valve lung volume reduction (ELVR) was performed in 12 patients with diffuse homogeneous form of emphysema. For ELVR valve used endobronchial valves MedLang. Patients who underwent ELVR included in the "core" group (n = 12). To compare the results has been allocated comparison group (n = 12), which included patients with diffuse homogeneous form of emphysema. Both groups were comparable for comparison.
Results: Dynamics of spirometric indices in the comparison group: FEV1 before surgical lung volume reduction 20,95±3,1 (%), after 31,08±2,7 (%); FVC before-27,32±10,12 (%), after 37,09±12,6 (%);
Spirometric indices in the comparison group: FEV1 before ELVR 15,94±5,38 (%), after 22,9±12,63 (%) (p=0,011);
FVC before-30,5±5,95 (%), after 30,23±11,07 (%)(p=0,858); FEV1/FVC to surgical lung volume reduction- 47,19±20,02, after- 72,0±17,54 (p=0,398).
In the comparison group: pO2 before surgical lung volume reduction- 58,08+-12,32, after 61,02±12,05; pCO2 before endobronchial valve – 40,72+-6,73, after-41,09+-5,48. Dynamics of parameters of blood gases in the study group. In the comparison group: pO2 before endobronchial valve lung volume reduction - 45,56±10,28 after52,7±9,99(p=0,013); pCO2 before endobronchial valve - 49,84±7,79, after- 44,0±5,42 (p=0,01).
Conclusion: Thus, in terms of up to 12 months of ELVR of lung volume reduction surgery and lung volume are comparable to the dynamics of indices of cardiorespiratory system, which may have important implications for the provision of surgical care "incurable" patients with COPD.
- © 2012 ERS