Markers | Before (FP) | After (FP) | Before (Placebo) | After (Placebo) |
% Rbm fragmentation | 19.1 (0.2-42.8)* | 2.6 (0-88.6)† | 24.0 (6.6-100) | 26.9 (2.5-48.5) |
S100A4 positive cells in BE per mm of Rbm | 25.8 (2.4-55.3)* | 12.3 (0.6-24.9)† | 19.8 (2.9-31.6) | 17.4 (10.3-35.5) |
S100A4 positive cells in Rbm per mm of Rbm | 44.4 (15.3-92.6)* | 20.8 (2.6-60.7)† | 23.1 (14-82.9) | 29.3 (3.6-48.1) |
MMP-9 positive cells in Rbm clefts per mm of Rbm | 0.6 (0-22.4)* | 0 (0-10.6)† | 1.1 (0-4.1) | 1.3 (0-2.7) |
EGFR % epithelium | 34 (14.6-59.5)* | 5.8 (2.6-43.8)† | 14.4 (3.6-38.2) | 10.3 (1.3-39.1) |