| Mean Rate of Decline mL/year, median (Q1,Q3) | |
| First exacerbation | |
| Before | After | P-value |
Pre-BD FEV1 | -27.5 (-101.1, 49.5) | -48.7 (-134.1, 22.2) | 0.0006 |
Post-BD FEV1 | -27.8 (-97.0, 41.7) | -59.0 (-132.7, 15.7) | 0.0002 |
Pre-BD FVC | -54.9 (-202.5, 99.8) | -61.1 (-230.3, 94.2) | 0.0403 |
Post-BD FVC | -58.6 (-187.3, 92.4) | -65.5 (-216.6, 61.2) | 0.0775 |