Abstract
Background: The COPD Assessment Test (CAT) is a valid and simple questionaire to quantify health status of COPD in routine clinical practice;therefore, it should play a role for detecting acute health status deterioration during monitoring visit.
Objective: To evaluated the discriminative properties of the CAT scores for detecting worsening and exacerbation of COPD patients in Thailand
Methods: The CAT questionaire was administered to 123 stable COPD patients attended at our chest clinic. These patients were monitored every 1-3 month interval for detecting worsening and exacerbation by using CAT score, physician and patient global assessment.
Results: A total of 237 visits among 123 patients, age 70.9±8.5 years, FEV1=47.9±18.4% predicted were followed. The mean score change in stable COPD was 0.28 (95%CI=-0.06-0.97) and 0.45 (95%CI=-0.06-0.97) by patient and physician global assessment. CAT scores were significantly higher at the time of worsening and exacerbation;the mean score changes were 5.97 (95%CI=4.68-7.24) and 9.25 (95%CI=6.70-11.79), respectively. The area under the ROC curve of CAT score for detection of acute health status deterioration was 0.92 (95%CI=0.88-0.96) and the cut-off point score at ≥12 had sensitivity, specificity and accuracy=76.74%,64.43% and 66.67%, respectively.
Conclusions: The CAT score change during monitoring visits is useful for detecting acute health status deterioration
- © 2011 ERS