Optimization of tissue targeting properties of macitentan, a new dual endothelin receptor antagonist, improves its efficacy in a rat model of pulmonary fibrosis associated with pulmonary arterial hypertension
Marc Iglarz, Kyle Landskroner, Daniel Wanner, Markus Rey, Patrick Hess, Martine Clozel
European Respiratory Journal 2011 38: p2292; DOI: