Abstract
Introduction: Auto-Servo Ventilation effectively suppresses Sleep Disordered Breathing (SDB) in patients with Congestive Heart Failure (CHF). This study compared the efficacy of a new mode of ASV that incorporates an automatic EPAP (ASV-Advanced), with and without its Bi-Flex comfort feature, to manually titrated ASV (ASV) in patients with central SDB and CHF.
Methods: Following diagnostic PSG and titration, patients underwent 3 consecutive treatment nights in a random order: ASV, ASV-Advanced and ASV-Advanced with Bi-Flex. For the ASV night, EPAP was set to the level determined during the titration night and IPAP set at EPAP+20cmH2O. For the ASV-Advanced nights, the device was set to automatically determine EPAP and IPAP pressures with a maximum pressure support of 20cmH2O. When activated, Bi-Flex was set to its maximum expiratory pressure relief. Data were analyzed with ANOVA and Bonferroni.
Results: 10 males participated (mean ± SD: age 67.4±11.7 y, BMI 28.4±5.5 kg/m2, LVEF 25.7±5.7%). Sleep time and efficiency were similar.
Conclusion: ASV-Advanced treats central SDB as effectively as ASV in patients with CHF.
- © 2011 ERS