| COPD subjects | Healthy subjects | p-value# |
Subjects n | 409 | 231 | |
Sex | | | 0.02 |
Female | 39.1 | 48.5 | |
Male | 60.9 | 51.5 | |
Age yrs | 63.6±6.9 | 54.7±8.5 | <0.01 |
Smoking habits | | | <0.01ƒ |
Never | 0.0 | 19.5 | |
Ex | 56.7 | 10.4 | |
Current | 43.3 | 70.1 | |
Comorbid heart disease¶ | | | <0.01 |
No | 79.5 | 96.1 | |
Yes | 20.5 | 3.9 | |
Medically treated hypertension | | | <0.01 |
No | 68.0 | 84.9 | |
Yes | 32.0 | 15.2 | |
Using regular platelet inhibitors | | | <0.01 |
No | 76.0 | 90.0 | |
Yes | 24.0 | 10.0 | |
Ever had depression requiring medical treatment | | | 0.02 |
No | 75.0 | 83.1 | |
Yes | 25.0 | 16.9 | |
GOLD category | | | |
II (FEV1 50–80) | 47.4 | 0 | |
III (FEV1 30–50) | 41.8 | 0 | |
IV (FEV1 0–30) | 10.8 | 0 | |
Experienced ▒2 exacerbations last year+ | | | |
No | 83.4 | | |
Yes | 16.6 | | |
Hypoxaemia (resting Pa,O2 <8.0)░ | | | |
No | 87.1 | | |
Yes | 12.9 | | |
Chronic cough | | | |
No | 53.6 | | |
Yes | 46.4 | | |
Dyspnoea grade III | | | |
No | 57.1 | | |
Yes | 42.9 | | |