Indication | Lesion aspirated | Cytology result | Outcome |
EBUS-TBNA | | | |
Known NSCLC. Enlarged 4R LNs on CT | 4R | NSCLC | N2 disease confirmed. Avoided mediastinoscopy. Chemotherapy |
Paraneoplastic syndrome. Solitary 10-mm 4R LN on CT | 4R | SCLC | Primary tissue diagnosis. Avoided mediastinoscopy. Chemotherapy |
Unknown small RLZ lesion. Subcarinal/precarinal LNs on CT | 3, 7 | NSCLC | Primary tissue diagnosis. N2 disease confirmed. Avoided mediastinoscopy. Supportive care |
Known NSCLC. Enlarged precarinal LN on CT | 3 | NSCLC | N2 disease confirmed. Avoided mediastinoscopy. Chemotherapy |
Known right side NSCLC. Enlarged 4R LNs | 4R | NSCLC | N2 disease confirmed. Avoided mediastinoscopy. Chemotherapy |
Isolated enlarged right paratracheal LNs | 2R, 4R | SCLC | Primary tissue diagnosis. Avoided mediastinoscopy. Chemotherapy |
Enlarged 4R LNs | 4R | NSCLC | Primary tissue diagnosis. Avoided mediastinoscopy. Chemotherapy |
Subcarinal mass lesion | 7 | NSCLC | Primary tissue diagnosis. Avoided mediastinoscopy. Chemotherapy |
Enlarged right hilar LNs. ? cause | 10R | Benign | Resolution on repeat CT. Reactive LN. True-negative EBUS-TBNA |
Known left NSCLC. Enlarged precarinal, subcarinal and left hilar LNs. ? malignant | 7, 10L | Benign | Resection staging pT2N0MX. True-negative EBUS-TBNA |
Right parabronchial lung mass. ? cause. No LNs enlarged on CT. Bronchoscopy normal | Mass lesion (EBUS appearance suggested malignancy) | Benign | Resection staging pT4N1MX. False-negative EBUS-TBNA |
Enlarged subcarinal, precarinal LNs | 7 | Benign | True-negative EBUS-TBNA for malignancy. Sarcoidosis following mediastinoscopy |
Enlarged subcarinal LNs | Station 7 EBUS appearance reactive | Not performed | Well following 1-yr follow-up. LNs presumed reactive secondary to infection |
Combined EBUS-TBNA/EUS-FNA | | | |
Enlarged 4R LNs. ? cause | 4R, 7 (EBUS). Postero-inferior 7 (EUS) | NSCLC | Primary tissue diagnosis. N2 disease confirmed. Avoided mediastinoscopy. Chemotherapy |
Enlarged 4R/subcarinal LNs. ? cause | 4R, 7 (EBUS). Postero-inferior 7 (EUS) | NSCLC | Primary tissue diagnosis. N2 disease confirmed. Avoided mediastinoscopy. Chemotherapy |
Widespread mediastinal LNs enlarged and pulmonary nodules | 4R, 7 (EBUS). 5, 7, mass lesion (EUS) | NSCLC | Primary tissue diagnosis. N2 disease confirmed. Avoided mediastinoscopy. Chemotherapy |
Left NSCLC. Enlarged precarinal/subcarinal and 4R LNs. ? N3 disease | 3 (4R LN was actually azygos vein) (EBUS). 7 (EUS) | Benign | Mediastinoscopy negative. Final resection staging T2N0. True-negative EBUS/EUS |
Known NSCLC. Enlarged subcarinal LNs | 7 (EBUS). 7 core biopsy (EUS) | Benign | Resection staging pT2N1M0. True-negative EBUS/EUS |
Small peripheral RLZ lesion. Enlarged right paratracheal/subcarinal LNs | 3, 4R, 7 (EBUS). 7 (EUS) | Benign | Mediastinoscopy negative for malignancy. Single 4R LN microfocus disease at thoracotomy. pT1N2. False-negative EBUS/EUS |
Left-sided NSCLC. No enlarged LNs on CT | No enlarged LNs seen. All appeared normal by EBUS/EUS | Not performed | Final resection T3N0. True-negative EBUS/EUS |