| Patient |
| 1 | 2 | 3 | 4 | 5 |
Age yrs | 49 | 54 | 68 | 63 | 55 |
Origin | White | White | White | White | White |
Sex | Male | Male | Male | Male | Male |
Nationality | German | German | German | Assyrian | German |
First diagnosis | 1996 | 1992 | 1996 | April 1999 | 1997 |
Previous therapy | Prednisolone since 1996, warfarin since 1992 | Prednisolone since 1997, azathioprine 1997– February 1998 | Prednisolone since 1997, cyclophosphamide 1997– 1998 | Prednisolone since 1999 | Prednisolone since 1997 |
Concomitant disease | Portal vein thrombosis due to protein C and AT III deficiency | Goiter | Myocardial infarction 1992, DVT 1988 | 1997 transurethral resection of prostate gland | None |
Smoking status | 20 pack-yrs until 1985 | 50 pack-yrs until 1986 | 50 pack-yrs until 1992 | Never smoked | Never smoked |
Profession | Businessman | Heating technician | College teacher | Army officer | Lawyer |
Treatment date with IFN‐γ1b | September 1997–January 1998 | May 1998–September 1998 | May 1998–May 1999 | January 2000–January 2001 | March 2000–June 2000 |
Special remarks | Sister died of probable IPF. Was listed for LTx and received a graft lung in 2000 | Was listed for LTx and received graft lung May 1999 | | Lost for follow-up | Was listed for LTx. Died after 3 months of therapy with IFN‐γ; autopsy findings and clinical data suggest right heart failure |
TLC at study entry L | 5.4 | 4.2 | 4.0 | 3.3 | 4.0 |
TLC at end of study L | 4.1 | 4.1 | 4.6 | 2.9 | 3.8 |
IVC at study entry L | 3.9 | 2.4 | 2.7 | 1.7 | 2.7 |
IVC at end of study L | 2.8 | 2.4 | 2.8 | 1.6 | 2.5 |
FEV1 at study entry L | 3.2 | 2.1 | 2.1 | 1.6 | 1.7 |