| Baseline | Final | Mean (95% CI) change from baseline after NIMV |
Pa,CO2 kPa | | | |
s-NIMV | 7.36±0.67 | 7.25±0.80 | |
NIMV | 7.57±0.80 | 6.45±0.53 | −1.12 (−1.52–−0.73) |
Pa,O2 kPa | | | |
s-NIMV | 6.56±0.80 | 6.73±0.80 | |
NIMV | 6.02±0.93 | 7.17±1.06# | 1.14 (0.70–1.50) |
V′E L·min−1 | | | |
s-NIMV | 10.10±3 | 10.28±2 | |
NIMV | 10.86±4 | 12.01±3* | 1.16 (0.05–2.28) |
VT, mL | | | |
s-NIMV | 552±147 | 543±133 | |
NIMV | 514±173 | 694±193¶ | 181 (110–252) |
ttot s | | | |
s-NIMV | 3.36±0.8 | 3.25±0.8 | |
NIMV | 2.95±0.8 | 3.62±1.1# | 0.67 (0.29–1.06) |
FEV1 % pred | | | |
s-NIMV | 37.6±11 | 36.7±11 | |
NIMV | 31.7±9 | 35.8±11# | 4.1 (1.5–6.9) |
FVC % pred | | | |
s-NIMV | 80±21 | 78±20 | |
NIMV | 71±17 | 80±18¶ | 9 (5–13) |
FEV1/FVC % | | | |
s-NIMV | 37.9±9 | 38.3±9 | |
NIMV | 36.6±10 | 37.1±12 | 0.5 (−1.7–2.8) |
FEF25–75% L·s−1 | | | |
s-NIMV | 0.25±0.08 | 0.24±0.08 | |
NIMV | 0.20±0.08 | 0.25±0.09# | 0.05 (0.015–0.076) |
TLC % pred | | | |
s-NIMV | 133±24 | 136±25 | |
NIMV | 127±24 | 117±23¶ | −10 (−13–−7) |
FRC % pred | | | |
s-NIMV | 171±41 | 175±42 | |
NIMV | 173±36 | 148±35¶ | −25 (−31–−18) |
RV % pred | | | |
s-NIMV | 201±55 | 209±51 | |
NIMV | 201±48 | 165±49¶ | −36 (−45–−27) |