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Eur Respir J 2007, doi:10.1183/09031936.00037106
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ORIGINAL ARTICLE |
Sleep apnoea in heart failure - results of a German survey
1 Universitätsklinikum Gießen/Marburg, Standort Gießen, Medizinische Klinik II
2 Charité Universitätsmedizin Berlin, Schlafmedizinisches Zentrum, Medizinische Klinik und Poliklinik, Schwerpunkt Kardiologie - Pulmologie - Angiologie
3 Universitätsklinik der Ruhr-Universität Bochum; St. Josefshospital, Medizinische Klinik II, Kardiologie and BG-Kliniken Bergmannsheil, Medizinische Klinik III (Pneumologie, Allergologie, Schlaf-und Beatmungsmedizin)
4 Sana Kliniken Ostholstein, Klinik Oldenburg, Innere Medizin-Pneumologie
5 Pius-Hospital Oldenburg/Niedersachsen, Klinik für Innere Medizin
6 Städtisches Krankenhaus Martha-Maria Halle-Dölau, Klinik für Innere Medizin II
7 Theresienkrankenhaus Mannheim, Abteilung Innere Medizin III
8 Universitätsklinikum Bonn, Medizinische Klinik II, Kardiologie/Pneumologie
9 Georg-August-Universität Göttingen, Zentrum für Innere Medizin, Abteilung Kardiologie/Pneumologie
* To whom correspondence should be addressed. E-mail: Richard.Schulz.
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Abstract |
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US-American studies have reported that sleep apnoea is common in congestive heart failure (CHF) with Cheyne-Stokes respiration (CSR) being the most frequent type of sleep-disordered breathing (SDB) in these patients. Within the present study, we sought to assess the prevalence and type of SDB among CHF patients in Germany.
203 CHF patients participated in this prospective multi-center study. All of them were stable in NYHA classes II and III and had a left ventricular ejection fraction (LVEF) < 40%. The patients were investigated by polygraphy and all data centrally analyzed. Patient enrollment was irrespective of sleep-related symptoms.
The majority of patients was hospitalized and of male gender, mean age was 65 years. 71% had an apnoea-hypopnoea-index >10·h-1 (n=145), obstructive sleep apnoea (OSA) occurred in 43% (n=88) and CSR in 28% (n=57).
The prevalence of SDB is high in stable severe CHF patients from a European population. As SDB may have a negative impact on the prognosis of CHF, a sleep study should be performed in every patient with CHF and a LVEF <40%. Probably, this diagnostic approach should be adopted for all of these patients irrespective of the presence of sleep-related symptoms.
Keywords: Cheyne-Stokes respiration, congestive heart failure, obstructive sleep apnoea
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