Eur Respir J 2007, doi:10.1183/09031936.00021507
Diagnosis of pulmonary embolism in hospitalized patients: retrospective survey of an institutional standard
1 Service de Pneumologie et d'Oncologie Thoracique
* To whom correspondence should be addressed. E-mail: stephanejouveshomme{at}chi-psg.com.
To assess the safety and implementation of a diagnostic strategy in hospitalized patients with suspected acute pulmonary embolism (PE). A diagnostic strategy was established and implemented in a general hospital. A retrospective cohort study including 400 consecutive inpatients was performed in order to assess the appropriateness of the diagnostic management and the incidence of symptomatic venous thromboembolic events (VTE) during follow-up. PE was confirmed in 116 patients (29%). The incremental value of adding compression ultrasonography (CUS) to multidetector-row CT (MDCT) for the diagnosis of PE was 8.6%. PE was appropriately excluded in 169 patients (42%) because of a normal lung scan (n=34), a negative MDCT providing an alternative diagnosis (n=94), a negative MDCT and CUS (n=41). During follow-up, VTE occurred in 3.5% patients. The almost unique cause of inappropriate management was the absence of further workup after a MDCT negative for PE providing no alternative diagnosis (n=115). Inappropriate management was associated with a non significant increased risk of VTE (7.2%) A frontline diagnostic work-up based on pulmonary MDCT associated with a CUS of the leg veins is effective and more sensitive than pulmonary MDCT alone in ruling out PE. Keywords: Compression ultrasonography, computed tomography, deep vein thrombosis, implementation study, pulmonary embolism
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