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Value of imprint cytology for ultrasound-guided transthoracic core biopsy

¹ Dept of Pathology, The Royal Liverpool University Hospital, Liverpool, and ² Chest Dept, Queen Mary's Hospital, Sidcup, UK

To the Editors:

Liao et al. 1 have shown that imprint cytology of ultrasound-guided transthoracic core biopsy is a sensitive procedure for diagnosing peripheral thoracic lesions. Similarly, we have recently reported the results of our experience of using touch imprint smears prepared from computerised tomographic-guided core needle lung biopsies 2. We correlated the cytological diagnosis of touch imprint smears with the histological diagnosis of the corresponding core needle-biopsy specimen, which was taken as the gold standard. There were no false-positive results, and all patients with small cell lung cancer were correctly diagnosed from the imprint smear. We agree that the technique is a quick, sensitive and highly specific method of detecting lung malignancies, and this may be particularly important with small cell lung cancer, where one may wish to start urgent chemotherapy pending the result of formal histology.

REFERENCES

1. Liao W-Y, Jerng J-S, Chen K-Y, Chang Y-L, Yang P-C, Kuo S-H. Value of imprint cytology for ultrasound-guided transthoracic core biopsy. Eur Respir J 2004;24:905–909.[Abstract/Free Full Text]
2. Paulose RR, Shee CD, Abdelhadi IA, Khan MK. Accuracy of touch imprint cytology in diagnosing lung cancer. Cytopathology 2004;15:109–112.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]

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