HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) All Versions of this Article: 33/2/389    most recent 09031936.00074208v1 Alert me when this article is cited Alert me if a correction is posted Permissions Request Permissions Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (4) Citing Articles via Google Scholar Google Scholar Articles by Koch, B. Articles by Gläser, S. Search for Related Content PubMed PubMed Citation Articles by Koch, B. Articles by Gläser, S.

Reference values for cardiopulmonary exercise testing in healthy volunteers: the SHIP study

¹ Dept of Cardiology, Pneumology and Infectious Diseases, ² Institute for Community Medicine, SHIP/Clinical-Epidemiological Research, University of Greifswald, Greifswald, ³ Dept of Cardiology, DRK-Kliniken Berlin/Westend, Berlin, Germany, ⁴ Both authors contributed equally to this article.

CORRESPONDENCE: B. Koch, Medical Faculty of the Ernst-Moritz-Arndt University, Dept of Pulmonary Medicine and Infectious Diseases, Friedrich-Loeffler-Str. 23, D-17475 Greifswald, Germany. Fax: 49 38348622422. E-mail: beate.koch{at}uni-greifswald.de

Keywords: Cardiopulmonary exercise testing, oxygen uptake, reference values, Study of Health in Pomerania, ventilatory efficiency

Received: May 15, 2008
Accepted August 20, 2008

Cardiopulmonary exercise testing (CPET) is a widely applied clinical procedure. The aim of the present study was to acquire a comprehensive set of reference values for cardiopulmonary responses to exercise and to evaluate possible associations with sex, age and body mass index (BMI).

A standardised progressive incremental exercise protocol on a cycle ergometer was applied to 1,708 volunteers of a cross-sectional epidemiologic survey, called "Study of Health in Pomerania". Individuals with cardiopulmonary disorders, or echocardiographic or lung function pathologies, were excluded. The influence of potential confounding factors, such as smoking, taking β-blockers, hypertension, diastolic dysfunction, BMI and physical activity, were analysed for their influencing power. Reference values of CPET parameters were determined by regression analyses.

Of the volunteers, 542 current smokers and obese individuals were excluded for not being representative of a healthy population. The final sample size was 534 (253 males), with age 25–80 yrs. The current study provides a representative set of reference values for CPET parameters based on age and weight.

Sex and age have a significant influence on exercise parameters. While addressing the problem of a selection bias, the current study provides the first comprehensive set of reference values obtained in a large number of healthy volunteers within a population-based survey.

This article has been cited by other articles:

				J. A. Neder On the issue of exercise normalcy Eur. Respir. J., July 1, 2009; 34(1): 286 - 287. [Full Text] [PDF]

				B. Koch, C. Schaper, H. Volzke, R. Ewert, and S. Glaser From the authors: Eur. Respir. J., July 1, 2009; 34(1): 287 - 288. [Full Text] [PDF]

				S. Glaser, C. Schaper, R. Ewert, and B. Koch Peak oxygen uptake and exercise capacity: a reliable predictor of quality of life? Eur. Heart J., July 1, 2009; 30(13): 1674 - 1674. [Full Text] [PDF]

				A. Gratz, J. Hess, and A. Hager Peak oxygen uptake and exercise capacity: a reliable predictor of quality of life?: reply Eur. Heart J., July 1, 2009; 30(13): 1674 - 1675. [Full Text] [PDF]