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Eur Respir J 2008; 31:887-890
Copyright ©ERS Journals Ltd 2008

The biology of oxygen

P. D. Wagner

CORRESPONDENCE: P. D. Wagner, Division of Physiology, Dept of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Fax: 1 8585344812. E-mail: pdwagner{at}ucsd.edu

Keywords: Hypoxia, hypoxic gene expression, O2 toxicity, O2 transport, tissue perfusion

Received: November 19, 2007
Accepted December 23, 2007

The biology of O2 is extremely complex and defies a comprehensive yet brief summary that showcases its roles across the entire animal and plant kingdom. This necessarily short introduction to the 2006 Taormina Lung Science Conference (Taormina, Italy) on hypoxia will examine key features of the biology of O2 only within mammalian cells, even that being a daunting task.






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