HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (13) Citing Articles via Google Scholar Google Scholar Articles by Dodge, J. A. Articles by Wilsher, J. Search for Related Content PubMed PubMed Citation Articles by Dodge, J. A. Articles by Wilsher, J.

Cystic fibrosis mortality and survival in the UK: 1947–2003

¹ Dept of Child Health, University of Wales Swansea, Swansea, and ² Dept of Mathematical Sciences, University of Bath, Bath, UK.

CORRESPONDENCE: J. A. Dodge, Dept of Child Health, University of Wales Swansea, Singleton Hospital, Sketty Road, Swansea SA2 8QA, UK. Fax: 44 1291671364. E-mail: j.a.dodge{at}btinternet.com

Keywords: Cystic fibrosis, epidemiology, expectation of life, survival

Received: July 31, 2006
Accepted November 27, 2006

Data up to 1995 on the survival of 3-yr cohorts of patients with cystic fibrosis (CF) born in the UK in the period 1968–1992 have previously been published. The present study reports survival data up to the end of 2003 together with a 2003 population estimate.

All subjects with CF born in the UK in the period 1968–1992 were identified up to 1997 by active enquiry through recognised CF clinics and other hospital consultants. Information from the death certification authorities up to the end of 2003 was added. Death certificates that could not be matched with UK Cystic Fibrosis Survey records were investigated and the data reconciled.

The observed survival up to 2003 of CF patients born in 1978 was 55% for males and 49% for females. For 1988 and 1992 the data were 91 and 88%, and 97 and 96%, respectively. The estimated 2003 mid-year CF population was 8,284.

The continuing improvement in survival of cystic fibrosis patients in successive cohorts means that the previous prediction of median survival of >50 yrs of age for individuals born in 2000 continues to look realistic, even in the absence of proven effective therapy aimed at correcting the basic cystic fibrosis defect.

This article has been cited by other articles:

				C. Glasscoe and J. A. Smith Through a Mother's Lens: A Qualitative Analysis Reveals How Temporal Experience Shifts When a Boy Born Preterm Has Cystic Fibrosis Clinical Child Psychology and Psychiatry, October 1, 2008; 13(4): 609 - 626. [Abstract] [PDF]

				A. von Drygalski and J. Biller Anemia in Cystic Fibrosis: Incidence, Mechanisms, and Association With Pulmonary Function and Vitamin Deficiency Nutr Clin Pract, October 1, 2008; 23(5): 557 - 563. [Abstract] [Full Text] [PDF]

				S. C L. Hewer and J. Tyrrell Cystic fibrosis and the transition to adult health services Arch. Dis. Child., October 1, 2008; 93(10): 817 - 821. [Full Text] [PDF]

				C. H Goss Should we stop using intravenous gentamicin in patients with cystic fibrosis? Thorax, June 1, 2008; 63(6): 479 - 480. [Full Text] [PDF]

				M. M. Tunney, T. R. Field, T. F. Moriarty, S. Patrick, G. Doering, M. S. Muhlebach, M. C. Wolfgang, R. Boucher, D. F. Gilpin, A. McDowell, et al. Detection of Anaerobic Bacteria in High Numbers in Sputum from Patients with Cystic Fibrosis Am. J. Respir. Crit. Care Med., May 1, 2008; 177(9): 995 - 1001. [Abstract] [Full Text] [PDF]

				I. M Balfour-Lynn Newborn screening for cystic fibrosis: evidence for benefit Arch. Dis. Child., January 1, 2008; 93(1): 7 - 10. [Full Text] [PDF]

				J. C Davies, E. W F W Alton, and A. Bush Cystic fibrosis BMJ, December 15, 2007; 335(7632): 1255 - 1259. [Full Text] [PDF]

				W. Lenney The future for lung disease in children Thorax, December 1, 2007; 62(12): 1021 - 1022. [Full Text] [PDF]