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1 Dept of Pathology and Laboratory Medicine, and 4 Dept of Pulmonology, University Medical Center Groningen, Groningen, and 2 Dept of Pulmonology, Leiden University Medical Center, Leiden, and 3 Netherlands Asthma Foundation, Leusden, The Netherlands.
CORRESPONDENCE: M. N. Hylkema, Dept of Pathology and Laboratory Medicine, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Fax: 31 503632510. E-mail: m.n.hylkema{at}path.umcg.nl
Keywords: Asthma, chronic obstructive pulmonary disease, cigarette smoke
Received: September 20, 2006
Accepted October 20, 2006
Smoking is the leading cause of preventable death worldwide. Hundreds of millions of individuals still smoke, affecting their health as well as that of their peers, family and offspring. Smoking is a well-established prime risk factor for chronic obstructive pulmonary disease and hampers the response to treatment in asthma and chronic obstructive pulmonary disease. In the present paper, new concepts are discussed with respect to pathology, treatment, smoking cessation and tobacco control. Recommendations for future directions are given.
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