ERJ
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (11)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Herth, F. J. F.
Right arrow Articles by Annema, J. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Herth, F. J. F.
Right arrow Articles by Annema, J. T.
Eur Respir J 2006; 28:1264-1275
Copyright ©ERS Journals Ltd 2006

Transbronchial and transoesophageal (ultrasound-guided) needle aspirations for the analysis of mediastinal lesions

F. J. F. Herth1, K. F. Rabe2, S. Gasparini3 and J. T. Annema2

1 Dept of Pulmonology and Critical Care Medicine, Thoraxklinik at the University of Heidelberg, Heidelberg, Germany, 2 Dept of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands, 3 Unit of Pulmonary Diseases, Dept of Internal Medicine, Immunoallergic and Respiratory Diseases, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Ancona, Italy.

CORRESPONDENCE: F. J. F. Herth, Dept of Pneumology and Critical Care Medicine, Thoraxklinik at the University of Heidelberg, Amalienstraße 5, D-69126 Heidelberg, Germany. Fax: 49 62213961202. E-mail: Felix.Herth{at}thoraxklinik-heidelberg.de

Keywords: Endobronchial ultrasound-guided transbronchial needle aspiration, transoesophageal ultrasound-guided fine needle aspiration, transbronchial needle aspiration

Received: January 30, 2006
Accepted September 25, 2006

A tissue diagnosis of mediastinal nodes is frequently needed for accurate lung cancer staging as well as the assessment of mediastinal masses. Transbronchial needle aspiration (TBNA) is a safe procedure that is performed during routine bronchoscopy. Provided mediastinal metastases are confirmed, TBNA has a high impact on patient management. Unfortunately, TBNA remains underused in current daily practice, mainly due to the lack of real-time needle visualisation. The introduction of echo-endoscopes has overcome this problem.

Endobronchial ultrasound-guided TBNA (EBUS-TBNA) allows real-time controlled tissue sampling of paratracheal, subcarinal and hilar lymph nodes. Mediastinal lymph nodes located adjacent to the oesophagus can be assessed by transoesophageal ultrasound-guided fine needle aspiration (EUS-FNA). Owing to the complementary reach of EBUS-TBNA and EUS-FNA in assessing different regions of the mediastinum, recent studies suggest that complete and accurate mediastinal staging can be achieved by the combination of both procedures.

It is expected that implementation of minimally invasive endoscopic methods of endobronchial ultrasound-guided transbronchial needle aspiration and transoesophageal ultrasound-guided fine needle aspiration will reduce the need for surgical staging of lung cancer significantly.




This article has been cited by other articles:


Home page
 JAMAHome page
M. B. Wallace
Lung Cancer Staging With Minimally Invasive Endoscopic Techniques--Reply
JAMA, June 4, 2008; 299(21): 2510 - 2511.
[Full Text] [PDF]

Home page
 ThoraxHome page
T Hishida, J Yoshida, M Nishimura, Y Nishiwaki, and K Nagai
Problems in the current diagnostic standards of clinical N1 non-small cell lung cancer
Thorax, June 1, 2008; 63(6): 526 - 531.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
F. J. F. Herth, R. Eberhardt, M. Krasnik, and A. Ernst
Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration of Lymph Nodes in the Radiologically and Positron Emission Tomography-Normal Mediastinum in Patients With Lung Cancer
Chest, April 1, 2008; 133(4): 887 - 891.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
M P Kennedy, C A Jimenez, J F Bruzzi, A D Mhatre, X Lei, F J Giles, T Fanning, R C Morice, and G A Eapen
Endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of lymphoma
Thorax, April 1, 2008; 63(4): 360 - 365.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
R. Milroy
Staging of Lung Cancer
Chest, March 1, 2008; 133(3): 593 - 595.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
K. G. Tournoy, F. De Ryck, L. R. Vanwalleghem, F. Vermassen, M. Praet, J. G. Aerts, G. Van Maele, and J. P. van Meerbeeck
Endoscopic Ultrasound Reduces Surgical Mediastinal Staging in Lung Cancer: A Randomized Trial
Am. J. Respir. Crit. Care Med., March 1, 2008; 177(5): 531 - 535.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
M. B. Wallace, J. M. S. Pascual, M. Raimondo, T. A. Woodward, B. L. McComb, J. E. Crook, M. M. Johnson, M. A. Al-Haddad, S. A. Gross, S. Pungpapong, et al.
Minimally Invasive Endoscopic Staging of Suspected Lung Cancer
JAMA, February 6, 2008; 299(5): 540 - 546.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by the European Respiratory Society.