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Cryptogenic organising pneumonia

Service de Pneumologie, Center des Maladies Orphelines Pulmonaires, Hôpital Cardiovasculaire et Pneumologique Louis Pradel, Lyon, France.

CORRESPONDENCE: J-F. Cordier, Dept of Respiratory Medicine, Reference Centre for Orphan Pulmonary Diseases, Louis Pradel University Hospital, 69677 Lyon (Bron), France. Fax: 33 472357653. E-mail: jean-francois.cordier{at}chu-lyon.fr

Keywords: Cryptogenic organising pneumonia

Received: February 8, 2005
Accepted November 22, 2005

Organising pneumonia is defined histopathologically by intra-alveolar buds of granulation tissue, consisting of intermixed myofibroblasts and connective tissue. Although nonspecific, this histopathological pattern, together with characteristic clinical and imaging features, defines cryptogenic organising pneumonia when no cause or peculiar underlying context is found. Rapid clinical and imaging improvement is obtained with corticosteroid treatment, but relapses are common after stopping treatment.

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