HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (4) Citing Articles via Google Scholar Google Scholar Articles by Hill, K. Articles by Eastwood, P. R. Search for Related Content PubMed PubMed Citation Articles by Hill, K. Articles by Eastwood, P. R.

High-intensity inspiratory muscle training in COPD

Depts of ¹ Pulmonary Physiology and, ² Physiotherapy, Sir Charles Gairdner Hospital, and ³ Asthma and Allergy Research Institute, and ⁴ School of Human Movement and Exercise Science, and, ⁵ School of Anatomy and Human Biology, University of Western Australia, Nedlands, and ⁶ School of Physiotherapy, Curtin University of Australia, Bentley, Australia.

CORRESPONDENCE: P. R. Eastwood, Dept of Pulmonary Physiology, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Western Australia, 6009 Australia, Fax: 61 893462034. E-mail: peter.eastwood{at}health.wa.gov.au

Keywords: Chronic obstructive pulmonary disease, inspiratory muscle training

Received: September 8, 2005
Accepted February 5, 2006

The aim of the present study was to investigate the effects of an interval-based high-intensity inspiratory muscle training (H-IMT) programme on inspiratory muscle function, exercise capacity, dyspnoea and health-related quality of life (QoL) in subjects with chronic obstructive pulmonary disease.

A double-blind randomised controlled trial was performed. Sixteen subjects (11 males, mean forced expiratory volume in one second (FEV₁) 37.4±12.5%) underwent H-IMT performed at the highest tolerable inspiratory threshold load (increasing to 101% of baseline maximum inspiratory pressure). Seventeen subjects (11 males, mean FEV₁ 36.5±11.5%) underwent sham inspiratory muscle training (S-IMT) at 10% of maximum inspiratory pressure. Training took place three times a week for 8 weeks and was fully supervised. Pre- and post-training measurements of lung function, maximum inspiratory pressure, maximum threshold pressure, exercise capacity, dyspnoea and QoL (Chronic Respiratory Disease Questionnaire; CRDQ) were obtained.

H-IMT increased maximum inspiratory pressure by 29%, maximum threshold pressure by 56%, 6-min walk distance by 27 m, and improved dyspnoea and fatigue (CRDQ) by 1.4 and 0.9 points per item, respectively. These changes were significantly greater than any seen following S-IMT.

In conclusion, high-intensity inspiratory muscle training improves inspiratory muscle function in subjects with moderate-to-severe chronic obstructive pulmonary disease, yielding meaningful reductions in dyspnoea and fatigue.

This article has been cited by other articles:

				T. J. Wilt, D. Niewoehner, R. MacDonald, and R. L. Kane Management of Stable Chronic Obstructive Pulmonary Disease: A Systematic Review for a Clinical Practice Guideline Ann Intern Med, November 6, 2007; 147(9): 639 - 653. [Abstract] [Full Text] [PDF]

				K. Hill, S. C. Jenkins, D. L. Philippe, K. L. Shepherd, D. R. Hillman, and P. R. Eastwood Comparison of incremental and constant load tests of inspiratory muscle endurance in COPD Eur. Respir. J., September 1, 2007; 30(3): 479 - 486. [Abstract] [Full Text] [PDF]