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1 Finnish Institute of Occupational Health, and 2 Environmental Epidemiology Unit, Dept ofPublic Health, University of Helsinki, Helsinki, Finland. 3 Institute of Occupational and Environmental Medicine, University of Birmingham, Birmingham, UK
CORRESPONDENCE: M.S. Jaakkola, Institute of Occupational and Environmental Medicine, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. Fax: 44 1214146028. E-mail: M.Jaakkola@bham.ac.uk
Keywords: Asthma, case-control study, smoking
Received: October 20, 2003
Accepted June 1, 2004
This study was supported by grants from the Finnish Ministry of Social Affairs and Health and the Finnish Work Environment Fund.
Studies on the effect of smoking on adulthood asthma have provided contradictory results. The current authors conducted a population-based incident case-control study to assess the effects of current and past smoking on the development of asthma in adults.
During a 2.5 yr study period, all new asthma cases clinically diagnosed (n=521) and randomly selected controls (n=932) from a geographically defined district in southern Finland were recruited.
The risk of developing asthma was significantly higher among current smokers with an adjusted odds ratio (OR) of 1.33 (95% confidence interval 1.00–1.77) and among ex-smokers with an adjusted OR 1.49 (1.12–1.97) compared with never-smokers. Among current smokers, the risk increased up to 14 cigarettes·day–1, and a similar trend was observed in relation to cumulative smoking.
In conclusion, the current results support the hypothesis that smoking causes asthma in adulthood.
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