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Relationship between exhaled air temperature and exhaled nitric oxide in childhood asthma

¹ Dept of Pediatrics, University of Verona and ² Dept of Cardiology, Istituto Pio XII, Misurina, Italy

CORRESPONDENCE: A.L. Boner, Dipartimento di Pediatria, Policlinico G.B. Rossi, 37134, Verona, Italy. Fax: 39 458200993. E-mail: boner,t;borgoroma.univr.it

Keywords: airway inflammation, asthma in childhood, exhaled air temperature, exhaled nitric oxide

Received: April 20, 2001
Accepted February 4, 2002

Airway inflammation is a characteristic of asthma. Exhaled nitric oxide (eNO) has been demonstrated to be related to actual levels of airway inflammation in asthmatic patients. The purpose of this study was to investigate whether the temperature of exhaled air is related to eNO levels.

Temperature of exhaled air and eNO were measured in 52 asthmatic children with a cross-sectional design.

A significant relationship was demonstrated between eNO and temperature of peak and plateau exhaled air temperature. The relationship between both the peak and the plateau values and eNO was more evident when it was corrected for environmental temperature.

These results suggest a relationship between exhaled nitric oxide and the temperature of exhaled air in asthmatic patients not treated with systemic steroids.

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