Copyright ©ERS Journals Ltd 2001 The SleepStripTM: an apnoea screener for the early detection of sleep apnoea syndrome1 Scientific Laboratory Products, Ltd., Tel Aviv, Israel. 2 Sleep Laboratory CHU A.Vésale, Free University of Brussels, Montigny-le-Tilleul, Belgium. 3 Med. Poliklinik of Philipps University, Marburg, Germany. 4 Sleep Laboratory, Technion-Israel Institute of Technology, Haifa, Israel CORRESPONDENCE: P. Lavie, Sleep Lab, Gutwirth Building, Technion City, Haifa, Israel, 32000. Fax: 972 48323045 Keywords: apnoeas, hypopnoeas, received-operator characteristic curves, screening, SleepStrip
Received: March 23, 2001
Conflict of interest: P. Lavie is the scientific advisor to the company manufacturing the SleepStrip. N. Hadas is the company's R&D manager. T. Shochat is the Clinical Trials Director of the company. P. Lavie and N. Hadas are both shareholders in the company.
Sleep apnoea syndrome (SAS) is a largely undiagnosed and prevalent disorder. It is associated with cardiovascular morbidity as well as excessive daytime sleepiness and poor quality of life. In the present study the SleepStripTM, a novel screening device is introduced, which is low cost and easy to use and is aimed for widespread use.
The results of three independent validation studies, which compared the SleepStripTM score (Sscore) against "gold standard" polysomnographically-determined apnoea/hypopnoea index (AHI), are reported both separately and combined. Four hundred and two patients suspected of SAS underwent full polysomnography recordings concomitantly with the use of the SleepStripTM.
For all samples combined, the correlation between AHI and Sscore was r=0.73, sensitivity and specificity values ranged from 8086% and 5786% respectively, and the area under the curve derived from receiver-operating characteristic curves ranged from 0.810.92 at varying AHI thresholds.
Though not intended as a substitute for polysomnography, the SleepStripTM may provide initial screening information, which may be useful in both clinical and experimental settings.
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