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Inflammatory endobronchial polyposis with bronchiectasis in cystic fibrosis

¹ Dept of Pathology, Aberdeen Royal Infirmary, ² Dept of Medical Paediatrics, Royal Aberdeen Children's Hospital and ³ Aberdeen Royal Infirmary, Aberdeen, UK

CORRESPONDENCE: K.M. Kerr, Dept of Pathology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZD, UK. Fax: 44 1224663002

Keywords: bronchiectasis, cystic fibrosis, polyp, polyposis

Received: January 18, 2001
Accepted March 13, 2001

Abstract

An unusual case of endobronchial polyposis associated with extensive bronchiectasis in the context of cystic fibrosis (CF) has been described.

A 15-yr-old female patient with CF underwent partial pneumonectomy for extensive bronchiectasis and frequent infective pulmonary exacerbations.

Cylindrical bronchiectasis with associated purulent bronchitis and bronchiolitis, together with inflammatory polyposis, was noted in the resected lung.

To the best of the authors' knowledge, this is the first report of multiple endobronchial polyposis and may represent a rare complication of bronchiectasis in a patient with cystic fibrosis. On-going infection and the cellular composition of the polyps are discussed in relation to their possible aetiological relevance and relationship to upper respiratory tract polyps.