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1 Dept of Paediatrics and 2 Laboratory of Pneumology, Katholieke Universiteit, Leuven, Belgium
CORRESPONDENCE: M. Demedts, Laboratory for Pneumology, U.Z. Gasthuisberg, Herestraat 49, B-3000, Leuven, Belgium. Fax: 016346803
Keywords: airway resistance, body plethysmography, forced oscillation technique, impulse oscillation system, impedance, reactance
Received: May 23, 2000
Accepted April 26, 2001
This study was funded by the National Fund for Scientific Research action "Care for Life", project numbers 7.0033.94, 7.0047.94 and 7.0078.94.
The impulse oscillation system (IOS) has been developed recently to measure respiratory system resistance (Rrs) and reactance (Xrs) at different frequencies up to
This study compared IOS with the classical pseudorandom noise forced oscillation technique (FOT) and body plethysmographic airway resistance (Raw) in 49 subjects with a variety of lung disorders and a wide range of Raw (0.101.28 kPa·L1·s).
Rrs,IOS was slightly greater than Rrs,FOT, especially at lower frequencies, with a mean±sd difference at 56 Hz of 0.14±0.09 kPa·L1·s. Comparisons with the wave-tube technique applied on two analogues indicated an overestimation by IOS. Xrs,IOS and Xrs,FOT were very similar, with a slightly higher resonant frequency with IOS than with FOT (mean difference±sd 1.35±3.40 Hz). Raw was only moderately correlated with Rrs-FOT and Rrs-IOS; although the mean differences were small (0.04±0.14 kPa·L1·s for Rrs6,FOT and 0.10±0.14 kPa·L1·s for Rrs5,IOS), IOS and FOT markedly underestimated high resistance values.
In conclusion, the impulse oscillation system yields respiratory system resistance and reactance values similar, but not identical to those provided by the forced oscillation technique.
25 Hz. IOS has, however, not been validated against established techniques.
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