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1 Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK. 2 Hadassah University Hospital, Mount Scopus, Kiryat Hadassah, Jerusalem, Israel. 3 Dept of Child Health, Clinical Sciences Building, Leicester Royal Infirmary, Leicester, UK. 4 Pulmonary Function Laboratories, Hadassah University Hospital, Jerusalem, Israel. 5 Section of Pulmonary Medicine, Children's Hospital, Colombus, OH, USA
CORRESPONDENCE: J. Stocks, Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK. Fax: 44 2078298634
Keywords: airways resistance, functional residual capacity, infant, methodology, respiratory function tests, standardization
Received: March 28, 2000
Accepted June 14, 2000
This
work was supported by a grant from the European Respiratory Society, and by
donations from GlaxoWellcome (UK) and GlaxoWellcome AB (Sweden).
Abstract
Functional residual capacity (FRC) is the only static lung volume
that can be measured routinely in infants. It is important for interpreting
volume-dependent pulmonary mechanics such as airway resistance or forced
expiratory flows, and for defining normal lung growth. Despite requiring complex
equipment, the plethysmographic method for measuring FRC is very simple to
apply and, unlike the gas dilution techniques, enables repeat measures of
lung volume to be obtained within a few minutes. This method has the further
advantage that with suitable adaptations to the equipment, simultaneous measurements
of airway resistance can also be obtained.
The aim of this paper is to provide recommendations pertaining to equipment
requirements, study procedures and reporting of data for plethysmographic
measurements in infants. Implementation of these recommendations should help
to ensure that such measurements are as accurate as possible and that meaningful
comparisons can be made between data collected in different centres or with
different equipment. These guidelines cover numerous aspects including terminology
and definitions, equipment, data acquisition and analysis and reporting of
results and also highlight areas where further research is needed before consensus
can be reached.
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