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Sleep apnoea and Turner's syndrome

¹ Dept of Respiratory Medicine, ² Sleep Laboratory, ³ Physiologie Respiratoire Experimentale Théorique et Appliquée (PRETA) Laboratory, ⁴ Dept of Maxillofacial and Plastic Surgery and ⁵ Dept of Radiology, Centre Hospitalier Universitaire de Grenoble

CORRESPONDENCE: J.L. Pépin, Sleep Laboratory and Respiratory Unit, University Hospital, BP 217 X, 38043 Grenoble, France. Fax: 33 476765617

A 32-yr-old female with Turner's syndrome and anatomical craniofacial abnormalities, presented with obstructive sleep apnoea syndrome. This was initially treated by nasal continuous positive airway pressure and secondarily cured by maxillomandibullar advancement osteotomy. Anatomical upper airway abnormalities and hormonal factors, which predispose Turner patients to develop obstructive sleep apnoea syndrome, are discussed. A systematic assessment and treatment of sleep-disordered breathing is probably of interest in these patients.

Keywords: cephalometry, obstructive sleep apnoea syndrome, Turner's syndrome, upper airway imaging