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Eur Respir J 1998; 12: 742-744
Copyright © ERS Journals Ltd 1998

Case Studies

A case of respiratory muscle weakness due to cytochrome c oxidase enzyme deficiency

A O'Brien, M Blaivas, J Albers, J Wald, and C Watts

Mitochondrial myopathy is a rare cause of dyspnoea and respiratory failure, usually presenting in infancy. We describe a 27 yr old woman with a partial cytochrome c oxidase enzyme deficiency causing respiratory muscle weakness and respiratory failure. The onset was acute, with no preceding respiratory symptoms. The patient was successfully treated with bilevel positive airway pressure therapy.


This article has been cited by other articles:


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 Am. J. Respir. Crit. Care Med.Home page
K. R. FLAHERTY, J. WALD, I. M. WEISMAN, R. J. ZEBALLOS, M. A. SCHORK, M. BLAIVAS, M. RUBENFIRE, and F. J. MARTINEZ
Unexplained Exertional Limitation . Characterization of Patients with a Mitochondrial Myopathy
Am. J. Respir. Crit. Care Med., August 1, 2001; 164(3): 425 - 432.
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