ERJ
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Taniere, P
Right arrow Articles by Berger, F
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Taniere, P
Right arrow Articles by Berger, F
Eur Respir J 1998; 12: 102-106
Copyright © ERS Journals Ltd 1998

Original Articles

Lymphomatoid granulomatosis--a report on four cases: evidence for B phenotype of the tumoral cells

P Taniere, F Thivolet-Bejui, D Vitrey, S Isaac, R Loire, JF Cordier, and F Berger

Four cases of lymphomatoid granulomatosis are reported, three of them involving the lung. Histological features included a true angiocentric and angiodestructive polymorphic cellular proliferation. This included histiocytes, plasma cells, many reactive T-cells and rare large, atypical cells which were of the B phenotype. Epstein-Barr virus was detected in the atypical cells by in situ hybridization in three cases, with expression of both latent membrane proteins (LMP)-1 and Epstein-Barr nuclear antigen-2 in two cases and expression of only LMP-1 in the third case. Expression of both of these proteins suggests a defect in the T-cell-mediated immunity and that Epstein-Barr virus is not only a silent passenger but may also be involved in the pathogenesis of the disease. This could have implications for therapy.


This article has been cited by other articles:


Home page
 J. Clin. Pathol.Home page
H-J Delecluse, R Feederle, B O'Sullivan, and P Taniere
Epstein Barr virus-associated tumours: an update for the attention of the working pathologist
J. Clin. Pathol., December 1, 2007; 60(12): 1358 - 1364.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Pathol.Home page
N. Salmons, R. J Gregg, A. Pallalau, I. Woolhouse, I. Geh, and P. Taniere
Lymphomatoid granulomatosis in a patient previously diagnosed with a gastrointestinal stromal tumour and treated with imatinib
J. Clin. Pathol., February 1, 2007; 60(2): 199 - 201.
[Full Text] [PDF]

Home page
 Eur Respir JHome page
S. Jaffre, F. Jardin, S. Dominique, E. Duet, Ph. Hubscher, A. Genevois, F. Corne, S. Bota, G. Nouvet, and L. Thiberville
Fatal haemoptysis in a case of lymphomatoid granulomatosis treated with rituximab.
Eur. Respir. J., March 1, 2006; 27(3): 644 - 646.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
J. Cadranel, M. Wislez, and M. Antoine
Primary pulmonary lymphoma
Eur. Respir. J., September 1, 2002; 20(3): 750 - 762.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
R. Summer, J. Zacks, M. Ieong, and A. O'Regan
Cough, fever and weight loss in a young male
Eur. Respir. J., June 1, 2002; 19(6): 1210 - 1213.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1998 by the European Respiratory Society.