ERJ
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Permissions
Right arrowRequest Permissions
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rodriguez-Panadero, F
Right arrow Articles by Antony, V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rodriguez-Panadero, F
Right arrow Articles by Antony, V.
Eur Respir J 1997; 10: 1648-1654
Copyright © ERS Journals Ltd 1997

Original Articles

Pleurodesis: state of the art

F Rodriguez-Panadero and VB Antony

Pleurodesis aims to achieve a symphysis between parietal and visceral pleural surfaces, in order to prevent accumulation of fluid or air in the pleural space. Its major indications are malignant effusions and pneumothorax, and a re-expandable lung is essential for the success of the technique. Moreover, expectation of a reasonably long survival is important before attempting pleurodesis. A successful lung re-expansion is unlikely if the pleural pressure falls more than 20 cmH2O x L(-1) of fluid removed, because there is a central bronchial obstruction or the lung is trapped by tumour and/or fibrin. Pleural fluid pH (<7.20) is a good indicator of the presence of trapped lung; moreover, a successful pleurodesis is less likely when pH is low, and this parameter is also a good predictor for survival of the patients. Among the many sclerosing agents that have been used for pleurodesis, talc has achieved the best results, with an average success rate of approximately 90%. The cellular and biochemical mechanisms involved in pleurodesis may be specific to the agent used, however, they may all follow a common final pathway leading to activation of the pleural coagulation cascade, the appearance of fibrin networks, and the proliferation of fibroblasts. The details of these mechanisms are still unclear and need to be further elaborated.


This article has been cited by other articles:


Home page
 Eur Respir JHome page
J-M. Tschopp, R. Rami-Porta, M. Noppen, and P. Astoul
Management of spontaneous pneumothorax: state of the art.
Eur. Respir. J., September 1, 2006; 28(3): 637 - 650.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
J. F. Montes, J. Garcia-Valero, and J. Ferrer
Evidence of Innervation in Talc-Induced Pleural Adhesions.
Chest, September 1, 2006; 130(3): 702 - 709.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
K. Psathakis, E. Calderon-Osuna, B. Romero-Romero, J. Martin-Juan, A. Romero-Falcon, and F. Rodriguez-Panadero
The neutrophilic and fibrinolytic response to talc can predict the outcome of pleurodesis.
Eur. Respir. J., April 1, 2006; 27(4): 817 - 821.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
M. E. Froudarakis, M. Klimathianaki, and M. Pougounias
Systemic inflammatory reaction after thoracoscopic talc poudrage.
Chest, February 1, 2006; 129(2): 356 - 361.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
E. Yildirim, K. Dural, R. Yazkan, N. Zengin, D. Yildirim, N. Gunal, and U. Sakinci
Rapid pleurodesis in symptomatic malignant pleural effusion
Eur. J. Cardiothorac. Surg., January 1, 2005; 27(1): 19 - 22.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
V. B. Antony, N. Nasreen, K. A. Mohammed, P. S. Sriram, W. Frank, N. Schoenfeld, and R. Loddenkemper
Talc Pleurodesis: Basic Fibroblast Growth Factor Mediates Pleural Fibrosis
Chest, November 1, 2004; 126(5): 1522 - 1528.
[Abstract] [Full Text] [PDF]

Home page
 J Ultrasound MedHome page
S. Sartori, P. Tombesi, D. Tassinari, P. Ceccotti, I. Nielsen, L. Trevisani, and V. Abbasciano
Sonographically Guided Small-Bore Chest Tubes and Sonographic Monitoring for Rapid Sclerotherapy of Recurrent Malignant Pleural Effusions
J. Ultrasound Med., September 1, 2004; 23(9): 1171 - 1176.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
N. A. Maskell, Y. C. G. Lee, F. V. Gleeson, E. L. Hedley, G. Pengelly, and R. J. O. Davies
Randomized Trials Describing Lung Inflammation after Pleurodesis with Talc of Varying Particle Size
Am. J. Respir. Crit. Care Med., August 15, 2004; 170(4): 377 - 382.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
B. H. Kwek, S. L. Aquino, and A. J. Fischman
Fluorodeoxyglucose Positron Emission Tomography and CT After Talc Pleurodesis
Chest, June 1, 2004; 125(6): 2356 - 2360.
[Abstract] [Full Text] [PDF]

Home page
 JCOHome page
S. Sartori, D. Tassinari, P. Ceccotti, P. Tombesi, I. Nielsen, L. Trevisani, and V. Abbasciano
Prospective Randomized Trial of Intrapleural Bleomycin Versus Interferon Alfa-2b via Ultrasound-Guided Small-Bore Chest Tube in the Palliative Treatment of Malignant Pleural Effusions
J. Clin. Oncol., April 1, 2004; 22(7): 1228 - 1233.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
J. F. Montes, J. Ferrer, M. A. Villarino, B. Baeza, M. Crespo, and J. Garcia-Valero
Influence of Talc Dose on Extrapleural Talc Dissemination after Talc Pleurodesis
Am. J. Respir. Crit. Care Med., August 1, 2003; 168(3): 348 - 355.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
O. Artemiou, G.-M. Marta, W. Klepetko, E. Wolner, and M.-R. Muller
Pleurovenous shunting in the treatment of nonmalignant pleural effusion
Ann. Thorac. Surg., July 1, 2003; 76(1): 231 - 233.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
J. E. Heffner, J. N. Heffner, and L. K. Brown
Multilevel and Continuous Pleural Fluid pH Likelihood Ratios for Evaluating Malignant Pleural Effusions
Chest, June 1, 2003; 123(6): 1887 - 1894.
[Abstract] [Full Text] [PDF]

Home page
 BMJHome page
J. Borchardt, A. Smirnov, L. Metchnik, and S. Malnick
Lesson of the week: Treating hepatic hydrothorax
BMJ, April 5, 2003; 326(7392): 751 - 752.
[Full Text] [PDF]

Home page
 Eur Respir JHome page
V.B. Antony
Immunological mechanisms in pleural disease
Eur. Respir. J., March 1, 2003; 21(3): 539 - 544.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
R. W. Light
Talc for Pleurodesis?
Chest, November 1, 2002; 122(5): 1506 - 1508.
[Full Text] [PDF]

Home page
 ChestHome page
A. Fraticelli, A. Robaglia-Schlupp, H. Riera, S. Monjanel-Mouterde, P. Cau, and P. Astoul
Distribution of Calibrated Talc After Intrapleural Administration: An Experimental Study in Rats
Chest, November 1, 2002; 122(5): 1737 - 1741.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
J. Ferrer, J. F. Montes, M. A. Villarino, R. W. Light, and J. Garcia-Valero
Influence of Particle Size on Extrapleural Talc Dissemination After Talc Slurry Pleurodesis*
Chest, September 1, 2002; 122(3): 1018 - 1027.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
G. W. Pien, M. J. Gant, C. L. Washam, and D. H. Sterman
Use of an Implantable Pleural Catheter for Trapped Lung Syndrome in Patients With Malignant Pleural Effusion
Chest, June 1, 2001; 119(6): 1641 - 1646.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
J. Ferrer, M. A. Villarino, J. M. Tura, A. Traveria, and R. W. Light
Talc Preparations Used for Pleurodesis Vary Markedly From One Preparation to Another
Chest, June 1, 2001; 119(6): 1901 - 1905.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
R. W. Light
Talc Should Not Be Used for Pleurodesis
Am. J. Respir. Crit. Care Med., December 1, 2000; 162(6): 2024 - 2026.
[Full Text]

Home page
 Am. J. Respir. Crit. Care Med.Home page
A. H. DIACON, C. WYSER, C. T. BOLLIGER, M. TAMM, M. PLESS, A. P. PERRUCHOUD, and M. SOLER
Prospective Randomized Comparison of Thoracoscopic Talc Poudrage under Local Anesthesia versus Bleomycin Instillation for Pleurodesis in Malignant Pleural Effusions
Am. J. Respir. Crit. Care Med., October 1, 2000; 162(4): 1445 - 1449.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
D. Bouros, M. Froudarakis, and N. M. Siafakas
Pleurodesis : Everything Flows
Chest, September 1, 2000; 118(3): 577 - 579.
[Full Text] [PDF]

Home page
 BMJHome page
G. J Peek, S. Morcos, and G. Cooper
Regular review: The pleural cavity
BMJ, May 13, 2000; 320(7245): 1318 - 1321.
[Full Text]

Home page
 ChestHome page
M. Glazer, N. Berkman, J. S. Lafair, and M. R. Kramer
Successful Talc Slurry Pleurodesis in Patients With Nonmalignant Pleural Effusion
Chest, May 1, 2000; 117(5): 1404 - 1409.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
N. NASREEN, K. A. MOHAMMED, P. A. DOWLING, M. J. WARD, G. GALFFY, and V. B. ANTONY
Talc Induces Apoptosis in Human Malignant Mesothelioma Cells In Vitro
Am. J. Respir. Crit. Care Med., February 1, 2000; 161(2): 595 - 600.
[Abstract] [Full Text]

Home page
 ChestHome page
J. E. Heffner, P. J. Nietert, and C. Barbieri
Pleural Fluid pH as a Predictor of Pleurodesis Failure* : Analysis of Primary Data
Chest, January 1, 2000; 117(1): 87 - 95.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1997 by the European Respiratory Society.